High level of anti helicobacter pylori heat shock protein 60II3, interferon Y, and neopterin are risk factors of cardiovascular events in acute coronary syndrome patients

Chronic inflammatory process that may cause acute myocardial infarction (AMI) has been known to play an important role in the pathogenesis of atherosclerosis and atheroma plaque instability. Based on inflammation process, several previous studies showed contradictory results in finding a relationship between infection H. pylori with the formation of atherosclerosis through the establishment of immunoglobulin G (IgG) anti-H. pylori-HSP60II3 (IgG anti-Hp-HSP60II3), and neopterin level due to oxidative stress. This study aims to know whether IgG anti-Hp-HSP60II3, IFN-? and neopterin are risk factors of cardiovascular events (CVE) in patients with ACS.