MECHANO-ACOUSTICAL STUDY OF PERFORATED TYMPHANIC MEMBRANE PATCH MODEL BASED ON CHITOSAN COMPOSITE MEMBRANE

Perforation patch scaffold organic model-based on chitosan through mechano-acoustical approach for assessing the perforation enclosure quality in terms of sound pressure quantity is the new inspiration of the perforation closure method.  The objective of this research was to develop a model of composite chitosan as a medical patch material of the tympanic membrane through mechanoacoustical approach. Chitosan composite membrane formulated with polyvinyl alcohol (PVA) only (A00), 3% chitosan-3% glycerol (B33), and 5% chitosan-1% glycerol (C51). The optimum formulation is obtained on composite chitosan, glycerol, and PVA with 3%/4%/5% ratio (B33) had characteristics of 622,29 kg/m3 in density, 160,70 µm in thickness, 1.43×10-2 g/mm a day in water vapor transmission rate. Mechanoacoustical test results of composite membranes with the formula had 0,30×106.N/m2 in Young's modulus; 0,18 cm-1 in sound absorption coefficient; 0,22×102 m/s in velocity on medium; 203,52 dBSPL in membrane sensitivity; and 94% of sound attenuation rate.