POTENTIALLY OF WATER EXCTRACT OF GYRINOPS VERSTEEGII LEAVES AS HERBAL MEDICINAL INGREDIENTS IN INCREASING BODY IMMUNITY

Increased body immunity by immunomodulatory substances in medicinal plants is the most important part of traditional medicine (alternative). Immunomodulators are substances that help the body to optimize the function of the immune system which plays a role in the body's defense from the influence of  free radicals and microorganisms such as bacteria, fungi and viruses. Several types of medicinal plants that have been investigated to have activities as immunomodulators are Beberapa jenis tanaman obat yang telah diteliti mempunyai aktivitas sebagai imunomodulator adalah Echinacea purpurea Echinacea purpurea, mengkudu (Morinda citrifolia L) , jahe (Zingiber officinale, meniran (Phyllanthus urinaria L,), pegagan (Centella asiatica) and sambiloto ( Andrographis paniculata. (Burm.f) Nees).  The immunomodulatory activity of this plant is caused by the content of its active compound, the phenolic compounds. Phenolic compounds that are widely contained in medicinal plants are Flavonoids.Flavonoids which are immunomodulatory are the flavones and flavonols. This immunomodulatory activity is inseparable from the antioxidant activity of phenolic compounds. The high content of flavonoid compounds namely flavonoid flavonol and very strong antioxidant activity and high levels of Vitamin C from water extracts (Gaharu leaves) can be used or developed as an alternative in increasing the body's immune or immunomodulatory at this time.