Journal article
The role of endothelial glycocalyx in sepsis
I Nyoman Budi Hartawan Made Wiryana
Volume : 3 Nomor : 1 Published : 2019, March
Bali Journal of Anesthesiology
Abstrak
The surface of endothelial cells is filled with various membrane-bound molecules that form the glycocalyx. The endothelial glycocalyx is a surface layer mainly consisted of glycosaminoglycans that include heparan sulfate, chondroitin sulfate, and hyaluronic acid and its core proteins. Previous studies suggest that endothelial surface glycocalyx shedding could play a role in endothelial dysfunction and inflammation. This article will review the endothelial glycocalyx and its role in sepsis.