Pengobatan gabapentin terhadap Postherpetic Neuralgia (PHN)

Background: Therapy for PHN includes preventing the presence of herpes zoster infection, which can be done by vaccination or treatment with antiviral drugs and specific therapies to treat pain in PHN. One therapeutic modality that is often used in the management of PHN is Gabapentin. Gabapentin belongs to the group of antiepileptic drugs that works by decreasing neural hyperexcitability which makes the published from 2000-2018. Manuscripts are collected from Google Scholar, PubMed, and the Cochrane Library. Results: There were 5 texts that matched the inclusion criteria. From the results of studies on PHN treatment, gabapentin has very good efficacy compared to placebo. There was no significant difference if gabapentin was compared with cryoanalgesia, although gabapentin drug effective in cases of neuropathic pain. had a slightly better efficacy (89.6% versus 86%). Method: The method used is a systematic review. The inclusion criterion is clinical trial research using gabapentin in response to PHN Conclusion: Gabapentin is a good treatment and has an important role for PHN treatment