Journal article

Predictors of Loss To Follow Up and Mortality Among Children 12 Years Receiving Anti Retroviral Therapy during the First Year at a Referral Hospital in Bali

Stefanie Juergen Anak Agung Sagung Sawitri Ketut Dewi Kumara Wati I Wayan Gede Artawan Eka Putra Ketut Tuti Parwati Merati

Volume : 4 Nomor : 2 Published : 2016, December

Public health and Preventive Medicine Archive

Abstrak

Abstract Background and purpose: Many HIV-infected children in Bali have started antiretroviral therapy (ART), but loss to follow up (LTFU) is a continuing concern, and the issue of childhood adherence is more complex compared to adults. Methods: This was a retrospective study among cohort of 138 HIV+ children on ART in Sanglah General Hospital, Denpasar, Bali from January 2010 to December 2015. Kaplan-Meier analysis was used to describe incidence and median time to LTFU/mortality and Cox Proportional Hazard Model was used to identify predictors. Variables which were analysed were socio-demographic characteristics, birth history, care giver and clinical condition of the children. Results: Mean age when starting ARV therapy was 3.21 years. About 25% experienced LTFU/death by 9.1 month resulting in an incidence rate of 3.28 per 100 child month. The higher the WHO stage, the higher the risk for LTFU/mortality along with low body weight (AHR=0.90; 95%CI: 0.82-0.99). Conclusion: Clinical characteristics were found as predictors for LTFU/mortality among children on ART. Keywords: Loss to follow up, mortality, paediatric, ART, Indonesia