Journal article

C-Reactive Protein and Interleukin-6 Correlated with Resistin Level in Liver Cirrhosis

I Ketut Mariadi hendra kuncoro I DEWA NYOMAN WIBAWA

Volume : 21 Nomor : 1 Published : 2020, April

The Indonesian Journal of Gastroenterology Hepatology and Digestive Endoscopy

Abstrak

The incidence of insulin resistance is very high in liver cirrhosis. Resistin is thought to be one of the factors contributing to the occurrence of insulin resistance. Liver Cirrhosis is a chronic inflammatory condition. CRP and IL6 are inflammatory mediators, which are associated with the severity of liver damage. Resistin also increases in liver cirrhosis. This study aimed to determine whether CRP and IL6 levels were correlated with resistin levels in patients with liver cirrhosis. An analytic cross-sectional study was conducted, in cirrhosis patients, to determine CRP and IL6 levels as markers of the inflammatory process and blood resistin levels. In this study was found, CRP and IL6 levels were associated with the severity of liver cirrhosis. Resistin levels are associated with the severity of cirrhosis of the liver. CRP and IL6 levels are positively correlated with resistin levels and as independent predictors of resistin levels. This study concluded that CRP and IL6 levels are correlated with resistin levels and as independent predictors of resistin levels in liver cirrhosis patients. Keywords: Resistin, CRP, IL-6, Liver Cirrhosis