COMPARISON OF RADIOGRAPHIC FEATURES OF EARLY AND FINAL THORAX RADIOGRAPHY WITH NEUTROFIL TO LYMPHOCYTE RATIO (NLR) IN COVID-19 CONFIRMED PATIENTS OF UDAYANA UNIVERSITY HOSPITAL, BALI, INDONESIA

Background: COVID-19 (Corona virus Disease 2019) is a disease that appears acute in the airways due to the SARS-CoV-2 virus (Severe Acute Respiratory Syndrome Coronavirus-2) and has been designated by WHO (World Health Organization) as a pandemic. The combination of radiological imaging and laboratory examination helps confirm the diagnosis of COVID-19. Damage to the pulmonary interstitial arteriolar wall depicts a picture of viral pneumonia on chest radiography showing an inflammatory response from a pathogenic virus. SARS-CoV2 plays an important role in the course of the disease. Neutrophil-to-Limfocyte Ratio (NLR) is an inflammatory biomarker that can cause a person's inflammatory process and immune status as well as a potential applicator that is very applicable and effective in determining the prognosis of COVID-19 patients.

Objective: To find out the initial and final thoracic radiographs with NLR in COVID-19 patients confirmed at Udayana University Hospital, Bali, Indonesia.

Method: This study used a comparative cross-sectional design that compared initial and final chest radiographic images with NLR <3.13 and ≥ 3.13. The study was conducted by analyzing secondary data from the medical records of 56 COVID-19 patients confirmed at Udayana University Hospital. The collected data will be analyzed univariately, bivariately, and multivariately using product statistics and service solutions (SPSS). In this study it is not expected that intervention on the subject and subject data will be kept confidential.

Conclusion: The results of this study will be used to make assessments related to the COVID-19 diagnosis rating system and help support the patient's prognosis.

Keywords: COVID-19, SARS-CoV-2, viral pneumonia, thoracic radiography, NLR.