CORRELATION BETWEEN GLOMERULAR FILTRATION RATE AND PARATHYROID HORMONE LEVELS IN PREDIALYSIS CHRONIC KIDNEY DISEASE PATIENTS

Chronic kidney disease (CKD) is a structural or functional abnormality in the kidneys for more than 3 months. Currently CKD has increased and become a serious health problem. In CKD predialysis, levels of parathyroid hormone in serum increase progressively since the early stages of the disease to maintain phosphate homeostasis. Glomerular Filtration Rate (GFR) has been widely accepted to assess kidney function. LFG assessment is used to determine the stage of CKD. This study wants to analyze the correlation between LFG and parathyroid hormone levels in predialysis CKD patients undergoing treatment at Sanglah Hospital Denpasar.

The purpose of this study was to determine and analyze the correlation between LFG and parathyroid hormone levels in predialysis CKD patients. The scientific benefit is giving information about correlation between LFG and parathyroid hormone levels in predialysis CKD patients so that it can be used for further research development, and the practical benefit of this study is giving information to health services/hospitals regarding the importance of evaluating parathyroid hormone levels to prevent and minimize complications of CKD.

This is an analytic observational study with a cross-sectional method in predialysis CKD patients undergoing treatment at Sanglah Hospital Denpasar who met the inclusion and exclusion criteria. Inclusion criteria were adult patients (≥ 18 years) who were willing to participate in the study. Exclusion criteria were predialysis CKD patients with liver disease. The levels of parathyroid hormone, BUN, creatinine and LFG were examined and the data obtained were analyzed with SPSS.