Primary Ovarian Non-Hodgkin's Lymphoma A Case Report of a 31-Year-Old of Bali Woman

Abstracts: Background: Primary ovarian Non-Hodgkin's lymphoma is a rare disease that is difficult to diagnose because it is often mistaken for ovarian cancer. Case presentation: A 31-year-old Bali woman presented abdominal pain for 2 days and experience weight loss. USG image showed a solid mass with multiple internal cystic components on the right adnexa, measuring the mass in the right adnexa 8.6 x 6.1 cm, suggesting a mass of the right ovary and para-aortic multiple lymphadenopathies. The patient underwent a complete blood count test, blood chemistry test, and tumor marker laboratory results showed an increase of cancer antigen 125 and lactate dehydrogenase, with normal value of cancer antigen 19-9, serum of ?-human chorionic gonadotropin, and alpha-fetoprotein. Minimal pleura effusion was also found on the left side. The patient diagnosed with a malignant ovarian tumor was planned for a USO-FZ laparotomy. Laparotomy was performed in the internal genitalia, a solid tumor originating from the right ovary, size 10 x 10 cm was found and the left ovary appeared to be 4 x 5 cm. Nine days after laparotomy, the diagnose showed a diffuse large B cell lymphoma. The patient was transferred to the hematology division and scheduled to undergo chemotherapy.Conclusion: Diagnosis is a crucial step in handling this case. Primary ovarian NHL is a difficult case to diagnose because it can be mistaken for other genital malignancies. Keywords: primary ovarian lymphoma, ovarian lymphoma, non-Hodgkin’s lymphoma, case report