THE ROLE OF MEDICATION REMINDER TECHNOLOGY AS AN ENHANCEMENT OF PATIENTS COMPLIANCE

Background: Medication compliance for patients with chronic diseases is still a hot issue to discuss. Low drug compliance contributes to treatment failure rates of up to 50%. Technology-based medicine reminder is starting to appear in the world community and is expected to be a solution to the problem of drug non-compliance. There is no comprehensive study related to the impact of this technology on patient drug compliance, so we need a special study to discuss this issue. Objective: The purpose of this study is to evaluate the effect of technology-based medicine reminders in improving patient drug compliance through systematic review and meta-analysis. Method: The collection of articles from a database related to technology-based medication reminders to increase compliance was carried out at 2010-2018 intervals. Google Scholar and two electronic databases, i.e., PUBMED and Science Direct, were used. After the articles were collected, the next step was the selection of eligible manuscripts, study quality assessment, data extraction, synthesis, and pooled analysis. Result: A total of 12 articles were analyzed and found that a technology-based medication reminder was able to influence patient medication compliance significantly. Pooled analysis result of risk ratio (RR) = 1.08 (CI95% 1.03-1.14) and mean difference (MD) = 0.70 (CI95% 0.65-0.75). Conclusion: Technology-based medication reminder is needed to deal with outpatients returning home with drugs to minimize therapeutic failure due to drug non-compliance. Keywords: Chronic Disease, Compliance, Medicine Reminder, Outpatients, Technology