Does dengue infection lead to persistent thrombocytopenia in hiv patient A report of two cases

Dengue infection commonly results in fatal outcome. We compare two different dengue infection outcomes in HIV infected children and desribe other factors related to outcome. First case: Dengue infection in 11-years-old HIV patient who has been with 1st line HAART for 3 years. On the 7th day, had persistent fever, low platelets, and neutropenia. To find out possible cause of this condition, we compared a similar case. Second case: Dengue Shock Syndrome in 6-years-old boy with HIV infection, who has been with HAART for 2 years. The clinical and laboratory resolved in 7 days. We investigated the old medical record of first patient and noticed prolonged pancytopenia with neutropenia. Macrocytic anemia began gradually since nine months after commencing ARV, hence working diagnosis was drug side effect either to zidovudine or cotrimoxazole. Cotrimoxazole was deceased and zidovudine was substituted with tenofovir. After one month follow up, the neutrophil, platelet, and hemogobin increased.