Journal article

Contributions of Herpes Simplex Virus 1 Envelope Proteins to Entry by Endocytosis

TRI KOMALA SARI Suzzane M. Pritchard Cristina W. Cunha George A. Wudiri Elizabeth I. Laws Hector C. Aguilar Naomi S. Taus Anthony V. Nicola

Volume : 87 Nomor : 24 Published : 2013, December

Journal of Virology

Abstrak

Herpes simplex virus (HSV) proteins specifically required for endocytic entry but not direct penetration have not been identified. HSVs deleted of gE, gG, gI, gJ, gM, UL45, or Us9 entered cells via either pH-dependent or pH-independent endocytosis and were inactivated by mildly acidic pH. Thus, the required HSV glycoproteins, gB, gD, and gH-gL, may be sufficient for entry regardless of entry route taken. This may be distinct from entry mechanisms employed by other human herpesviruses.

Related Publication

Glycoprotein C of Herpes Simplex Virus Shields Glycoprotein B from Antibody Neutralization

TRI KOMALA SARI Katrina A. Gianopulos Anthony V. Nicola

Jurnal Internasional Terindeks... 2020

Herpes Simplex Virus Glycoprotein C Regulates Low-pH Entry

TRI KOMALA SARI Katrina A. Gianopulos Darin J. Weed Seth M. Schneider Suzzane M. Pritchard Anthony V. Nicola

Jurnal Internasional Terindeks... 2020

Acidic pH Mediates Changes in Antigenic and Oligomeric Conformation of Herpes Simplex Virus gB and Is a Determinant of Cell-Specific Entry

Darin J. Weed Stephen J. Dollery TRI KOMALA SARI Anthony V. Nicola

Jurnal Internasional Terindeks... 2018

Widely Used Herpes Simplex Virus 1 ICP0 Deletion Mutant Strain dl1403 and Its Derivative Viruses Do Not Express Glycoprotein C Due to a Secondary Mutation in the gC Gene

Cristina W. Cunha Kathryne E. Taylor Suzzane M. Pritchard Mark G. Delboy TRI KOMALA SARI Hector C. Aguilar Karen L. Mossman Anthony V. Nicola

Jurnal Internasional Terindeks... 2015