FORMULASI SEDIAAN KRIM ANTI LUKA BAKAR DARI EKSTRAK AIR DAGING DAUN ALOE VERA

ABSTRAK Lidah buaya (Aloe vera) merupakan salah satu tanaman yang secara empiris sering digunakan untuk menyembuhkan luka bakar. Ekstrak air daging daun Aloe vera mengandung saponin dan flavonoid, di samping itu juga mengandung tanin dan polifenol. Penelitian ini dilakukan untuk mengetahui apakah ekstrak air daging daun aloe vera yang diperoleh telah memenuhi parameter standar mutu ekstrak sehingga dapat digunakan dalam formulasi. Tahapan yang dilakukan yaitu ekstraksi daging daun aloe vera dengan metode maserasi infundasi, Standarisasi ekstrak air daging lidah buaya meliputi pengujian penetapan susut pengeringan, kadar abu total, penetapan kadar abu tidak larut dalam asam, penetapan kadar sari yang larut dalam air, penetapan kadar sari yang larut dalam etanol dan skrining fito kimia, identifikasi dengan FT-IR, pembuatan sediaan krim, evaluasi sediaan krim. Ekstrak air daging daun lidah buaya diperoleh dengan teknik infudasi. Pengujian susut pengeringan ekstrak yang dihasilkan sebesar 26,33 %, kadar abu total sebesar 1,3%, kadar sari larut dalam air sebesar 11,9% dan kadar sari larut etanol 12,01%, kadar flavonoid total sebesar 2,9%. Kata kunci: Aloe Vera, Formulasi, Krim, Luka Bakar. ABSTRACT Aloe vera (Aloe vera) is a plant that is empirically often used to heal burns. Aloe vera leaf meat water extract contains saponins and flavonoids, in addition it also contains tannins and polyphenols. This research was conducted to determine whether the extracted water of Aloe vera leaf meat had met the parameters of extract quality standards so that it could be used in formulations. The steps taken are the extraction of aloe vera leaf meat with the method of infundation maceration, standardization of Aloe vera meat water extraction including testing the determination of drying shrinkage, total ash content, determination of ash content which is insoluble in acid, determination of the essence of water soluble extract, determination of the extract soluble in ethanol and chemical screening, identification with FT-IR, preparation of cream preparations, evaluation of cream preparations. Aloe vera leaf meat extract was obtained by infudation technique. Tests for drying drying extract produced 26.33%, total ash content of 1.3%, water soluble extract content of 11.9% and ethanol soluble extract content of 12.01%, total flavonoid content of 2.9%. Keywords: Aloe Vera, Formulation, Cream, Burns.