Journal article
ASSESSMENT OF LIFE QUALITY OF CERVICAL CANCER PATIENTS DELIVERED BLEOMYCIN ONCOVIN MITOCYN PLATINUM (BOMP) CHEMOTHERAPY REGIMENS IN SANGLAH DENPASAR
RINI NOVIYANI I Nyoman Gede Budiana PUTU AYU INDRAYATHI
Volume : 2 Nomor : 2 Published : 2015, April
International Journal of Biosciences and Biotechnology
Abstrak
Cervical cancer disease is one of cancers that attack many women in the world and ranks second after breast cancer. Symptoms of cervical cancer may cause degradation quality of patients life. Chemotherapy is one of treatments of cervical cancer patients. Chemotherapy provides therapeutic effects, however, it can causes a decrease in life quality due to its side effects. BOMP is one of regimens that can be used as one of the management of cervical cancer. Assessment of quality of patients life with cervical cancer are needed to see the changes in the quality of life in patients besides knowing the functional status changes from time to time. Monitoring the effects of treatment, and collecting the data on quality of life can be used as initial data for consideration in formulating the appropriate action for the patient, And also assist physicians in selecting an effective and well tolerated drug for patients.The study was conducted in February to June 2014 in Obstetrics Clinic and Cempaka Timur Room General Hospital (RSUP) Sanglah in observational design with cross sectional prospective. The sample selection is done by consecutive sampling. The methods used for data collection using questionnaires EORTC QLQ with interview techniques before and after chemotherapy in patients suffering cervical cancer of squamous cell stage IIB - IIIB who had BOMP chemotherapy regimens for 3 series in RSUP Sanglah. Research for quality of life is conducted in general and the 15 domains that affect the quality of life of patients. In this study, 12 patients indicated the inclusion criteria. There were significant differences in the value of the quality of life of patients with cervical cancer squamous cell stage IIB - IIIB before and after BOMP chemotherapy with 0.001 p value. BOMP chemotherapy regimens can improved the quality of life of cervical cancer patients increasing from 44.833 ± 6.235 to 60.333 ± 9.168. In 15 ratings domain included decrease the quality of life of pain domain, nausea domain, vomiting domain, decreased appetite domains, fatigue domain, physical function domain, functional role domain, social functioning domain, sleeplessness domain, constipation domain and domain of financial difficulties and on the other hand emotional domain increase. Keywords: Cervical cancer, quality of life, BOMP regimen, the domain of quality of life.