Journal article

Encapsulated liposome toward anthocyanin in pectin-based dry jelly as a breakthrough therapeutic management in pediatric obesity literature review

putu nandika tungga yudanti mahardani komang diah kurnia kesumaputri i gede wikania wira wiguna Dyah Kanya Wati

Volume : 11 Nomor : 1 Published : 2020, January

intisari sains Medis

Abstrak

Background: In the globalization era, the high number of obesities is happened to the teenagers because of the unhealthy life-style. Obesity in the teenagers or pediatric obesity is important to be handled because it can trigger another complication that happened in the early age. This study aims to collect and analyze any source related to anthocyanin (ASN) from purple sweet potato (Ipomoea batatas L) as modality of obesity that is packaged as dry jelly. Methods: A literature search strategy was conducted to obtained eligible source of study such as books and journals from Google Scholar, Research Gate, and PubMed. The criteria of eligible literature used in this study were articles published on 1981-2019 from different type of study. About 73 literature were used as references regarding the potency of ASN from purple sweet potato (Ipomoea batatas L) as the modality for obese people. Results: ASN in the purple sweet potato has anti-obesity effect by decreasing the a-glucosidase enzyme and a-amylase, increasing glucagon-like-peptide-1 and peptide YY, changing the size of adipose cell, decreasing the lipogenic activity and inflammation, increasing the lipolysis and ?-oxyanion adipose cell, as well as increasing the concentrate of brain-derived neutrophil factor in a brain. To increase the bioavailability of ASN, it has to be done the encapsulation with liposome base. Modality is packaged in the dry jelly form with pectin base as a formulation in powder form taken orally. The modality consumption is 24 mg/kg of weight, however, after eating, the obese people tend to give the weight decreasing effect and cross section attractive to target modalities. Conclusion: According to the studies, the ASN from purple sweet potato and package in Pectin-Based Dry Jelly could be used as a novel strategy in managing the pediatric obesity. Keywords: Anthocyanin, dry jelly, pectin, pediatric obesity, purple sweet potato. Cite This Article: Mahardani, P.N.T.Y., Kesumaputri, K.D.K., Wiraguna, I.G.W.W., Wati, D.K. 2020. Encapsulated liposome toward anthocyanin in Pectin-Based Dry Jelly as a breakthrough therapeutic management in pediatric obesity: a literature review. Intisari Sains Medis 11 (1): 1-8. DOI: 10.15562/ism.v11i1.524