The Influence of Granting Ngor Eggplant (Solanium Indicum) Extract inhibiting of Spermatogenesis in Mice (Mus Musculus)

The study about contraceptive for adult especially for men that the numbers were limited, so needed the ingredients contraceptive is derived from a plant. One of the plants that potentially becomes contraceptive is ngor eggplant because contains antifertility substances. The research has been done about granting of ngor eggplant extract inhibiting spermatogenesis in mice. The design of research used random post-test control group design by one group control, three groups by treatment and six times doing treatment again. (T0 = control group, T1 = granting extract 15%, T2 = granting extract 20%, T3 = granting extract 25%). This treatment has been done in 36 days. The result of this research showed the granting ngor eggplant extract to T1 could reduce the number of cells spermatocyte primary pakhiten and cells spermatids 7 & 19 by meaningful (P<0,05). In T2 and T3 could reduce the number spermatogonia A cells, spermatocyte primary pakhiten cells and spermatids 7 & 19 cells (P<0,05).